Recombinant Human MOG Protein (E.coli, His Tag)

Product Specifications

Background

Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein; which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals; namely experimental autoimmune encephalomyelitis (EAE) ; in rodents and monkeys.

Abbreviation

MOG

Synonyms

BTN6; BTNL11; MOG; MOGIG2; Myelin-Oligodendrocyte Glycoprotein; NRCLP7

UniProt

Q16653

Accession Number

Q16653

Expression System

E.coli

Tag

C-His

Sequence

Gly30-Gly154

Field of Research

Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.