Recombinant Human MOB1A Protein (His Tag)

Product Specifications

Background

MOB Kinase Activator 1A (MOB1A) belongs to the MOB1/phocein family, which acts as an activator of LATS1/2 in the Hippo signaling pathway, plays a key role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. MOBKL1B stimulates the kinase activity of STK38 and STK38L. MOBKL1B binds to and regulate downstream targets such as the NDR-family protein kinases and LATS1 kinase.

Abbreviation

MOB1A

Synonyms

C2orf6; MOB Kinase Activator 1A; MOB1A; MOB4B; MOBK1B; MOBKL1B; Mob1 Alpha; Mob1 Homolog 1B; Mob1A; Mps One Binder Kinase Activator-like 1B

UniProt

Q9H8S9

Accession Number

Q9H8S9

Expression System

E.coli

Tag

C-His

Sequence

Ser2-Arg216

Field of Research

Signal Transduction; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.