Recombinant Human MECP2 Protein (His Tag)
Product Specifications
Background
The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein is present in cells throughout the body, although it is particularly abundant in brain cells.In the brain, the MeCP2 protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. The alternative splicing of proteins is critical for normal communication between neurons and may also be necessary for the function of other types of brain cells.
Abbreviation
MECP2
Synonyms
MECP2; MeCp-2 protein; Methyl-CpG-binding protein 2
UniProt
P51608
Accession Number
P51608
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met 1-Ser486
Field of Research
Neuroscience; epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/88tyah
Product MSDS
https://789.bio/eb/CK0u1S
Calculated Molecular Weight
53.5 kDa
Observed Molecular Weight
90 kDa
Species
Human
Available Sizes
Curated Selection
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