Recombinant Human MAP1D Protein (His Tag)
Product Specifications
Background
Methionine Aminopeptidase 1D (METAP1D) is a mitochondrion protein that belongs to the peptidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.
Abbreviation
MAP1D
Synonyms
MAP 1D; MAP1D; METAP1D; MetAP 1D; Metap1l; Methionine Aminopeptidase 1D Mitochondrial; Methionyl Aminopeptidase Type 1D Mitochondrial
UniProt
Q6UB28
Accession Number
Q6UB28
Expression System
E.coli
Tag
N-His & C-His
Sequence
Arg44-Ala335
Field of Research
Signal Transduction; epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
35.4 kDa
Observed Molecular Weight
35-40 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.
Species
Human
Available Sizes
Documents
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