Recombinant Human MGAT2/GlcNAc-TII Protein (His Tag)
Product Specifications
Background
Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.
Abbreviation
MGAT2; GlcNAc-TII
Synonyms
2-N-acetylglucosaminyltransferase II;6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase; Alpha-1; Beta-1; GlcNAc-T II; MGAT2; Mannoside Acetylglucosaminyltransferase 2; N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II; NT-II
UniProt
Q10469
Accession Number
Q10469
Expression System
HEK293 Cells
Tag
C-His
Sequence
Arg30-Gln447
Field of Research
Tags & Cell Markers
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
49.3 kDa
Observed Molecular Weight
50 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Species
Human
Available Sizes
Documents
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