Recombinant Human MAA/GSTZ1 Protein (His Tag)
Product Specifications
Background
Maleylacetoacetate Isomerase (MAAI) belongs to the Glutathione S-Transferase super-family. MAAI encodes multifunctional enzymes in the detoxification of electrophilic molecules by conjugation with glutathione, for example, mutagens, carcinogens and several therapeutic drugs. MAAI is a bifunctional protein with low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. MAAI can catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. But it has minimal glutathione-conjugating activity with 7-chloro-4-nitrobenz-2-oxa-1, ethacrynic acid 3-diazole and maleylacetoacetate isomerase activity.
Abbreviation
MAA; GSTZ1
Synonyms
GSTZ1; GSTZ1-1; Glutathione S-Transferase Zeta 1; MAAI; Maleylacetoacetate Isomerase
UniProt
O43708
Accession Number
O43708
Expression System
E.coli
Tag
C-His
Sequence
Met 1-Ala216
Field of Research
Signal Transduction; Tags & Cell Markers; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
25.2 kDa
Observed Molecular Weight
25-30 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 1mM DTT, pH 8.0.
Species
Human
Available Sizes
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