Recombinant Human LTBR/TNFRSF3 Protein (His Tag)
Product Specifications
Background
Tumor necrosis factor receptor superfamily member 3; also known as Lymphotoxin-beta receptor; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor type III; LTBR; TNFCR; TNFR3 and TNFRSF3; is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types; but not on T and B lymphocytes. LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of LTBR can trigger apoptosis. In addition; LTBR can lead to the release of the cytokine interleukin 8.
Abbreviation
LTBR; TNFRSF3
Synonyms
D12S370; LTBR; Lymphotoxin-Beta Receptor; TNF-RIII; TNFCR; TNFR-III; TNFR3; TNFRSF3; Tumor Necrosis Factor C Receptor; Tumor Necrosis Factor Receptor 2-Related Protein; Tumor Necrosis Factor Receptor Superfamily Member 3; Tumor Necrosis Factor Receptor Type III
UniProt
P36941
Accession Number
P36941
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gln31-Met227
Field of Research
Signal Transduction; Cell biology; epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/00vym5
Product MSDS
https://789.bio/eb/ivvPiD
Calculated Molecular Weight
22.8 kDa
Observed Molecular Weight
29-40 kDa
Species
Human
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items