Recombinant Human LTA4H Protein (His Tag)
Product Specifications
Background
LTA4H, which is short for Leukotriene A-4 hydrolase, is a 611 aa. protein. It belongs to the peptidase M1 family, and exists in cytoplasm. This protein has at least 4 isforms produced by alternative splicing, and two of them are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts. LTA4H involves in lipid metabolism and leukotriene B4 biosynthesis. It is a epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. It also has aminopeptidase activity
Abbreviation
LTA4H
Synonyms
LTA-4 hydrolase; LTA4; LTA4H; Leukotriene A (4) hydrolase; Leukotriene A-4 hydrolase
UniProt
P09960
Accession Number
P09960
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met 1-Asp611
Field of Research
Cancer; immunology; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
70.3 kDa
Observed Molecular Weight
60-70 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM MES, 2mM EDTA, 20% Glycerol, pH 5.0.
Species
Human
Available Sizes
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