Recombinant Human LMIR2/CD300C Protein (Fc Tag)

Product Specifications

Background

CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells; granulocytes; most myeloid cells; dendritic cells; and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.

Abbreviation

LMIR2; CD300C

Synonyms

CD300 Antigen-Like Family Member C; CD300C; CD300c; CLM-6; CMRF-35; CMRF35; CMRF35-A1; CMRF35-Like Molecule 6; CMRF35A; CMRF35A1; IGSF16; IgSF16; Immunoglobulin Superfamily Member 16

UniProt

Q08708

Accession Number

Q08708

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Gly21-Arg183

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.