Recombinant Human CD300a/LMIR1 Protein (His Tag)
Product Specifications
Background
CD300A is a single-pass type I membrane protein that belongs to the CD300 family. CD300A consists of a 163 amino acid (aa) extracellular domain (ECD) with one Ig-like V- type domain; a 21 amino acid transmembrane segment; and a 98 amino acid cytoplasmic domain with tyrosine residues. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets; B-cells; dendritic cells; mast cells; granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells; and to the down-regulation of mast cell degranulation.
Abbreviation
CD300a; LMIR1
Synonyms
CD300 Antigen-Like Family Member A; CD300A; CD300a; CLM-8; CMRF-35-H9; CMRF35-H; CMRF35-H9; CMRF35-Like Molecule 8; CMRF35H; IGSF12; IRC1/IRC2; IRp60; IgSF12; Immunoglobulin Superfamily Member 12; Inhibitory Receptor Protein 60; NK Inhibitory Receptor
UniProt
Q9UGN4
Accession Number
Q9UGN4
Expression System
HEK293 Cells
Tag
C-His
Sequence
Leu18-Gln178
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/isgzqd
Product MSDS
https://789.bio/eb/rLq5KG
Calculated Molecular Weight
18.5 kDa
Observed Molecular Weight
23-37 kDa
Species
Human
Available Sizes
Curated Selection
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