Recombinant Human CD300a/LMIR1 Protein (His Tag)

Product Specifications

Background

CD300A is a single-pass type I membrane protein that belongs to the CD300 family. CD300A consists of a 163 amino acid (aa) extracellular domain (ECD) with one Ig-like V- type domain; a 21 amino acid transmembrane segment; and a 98 amino acid cytoplasmic domain with tyrosine residues. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets; B-cells; dendritic cells; mast cells; granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells; and to the down-regulation of mast cell degranulation.

Abbreviation

CD300a; LMIR1

Synonyms

CD300 Antigen-Like Family Member A; CD300A; CD300a; CLM-8; CMRF-35-H9; CMRF35-H; CMRF35-H9; CMRF35-Like Molecule 8; CMRF35H; IGSF12; IRC1/IRC2; IRp60; IgSF12; Immunoglobulin Superfamily Member 12; Inhibitory Receptor Protein 60; NK Inhibitory Receptor

UniProt

Q9UGN4

Accession Number

Q9UGN4

Expression System

HEK293 Cells

Tag

C-His

Sequence

Leu18-Gln178

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.