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Recombinant Human LILRA2/ILT1 Protein (His Tag)

Product Specifications

Background

Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 2 (LILRA2) is a single-pass type I membrane protein. LILRA2 is expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. LILRA2 contains four Ig-like C2-type domains, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. LILRA2 does not bind class I MHC antigens.

Abbreviation

LILRA2; ILT1

Synonyms

CD85 Antigen-Like Family Member H; CD85h; ILT-1; ILT1; Immunoglobulin-Like Transcript 1; LILRA2; LIR-7; LIR7; Leukocyte Immunoglobulin-Like Receptor 7; Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 2

UniProt

Q8N149

Accession Number

Q8N149-2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gly24-Ser420

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

44.8 kDa

Observed Molecular Weight

66 kDa

Species

Human

Available Sizes

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