Recombinant Human LCAT Protein (His Tag)

Lipase family. The gene encoding this protein is expressed mainly in brain, liver and testes, followed by secreting into plasma and cerebral spinal fluid. The esterification of cholesterol is required for cholesterol transport. LCAT is a central enzyme in the extracellular metabolism of plasma lipoproteins. Defects in LCAT are the cause of lecithin-cholesterol acyltransferase deficiency (LCATD) and a cause of fish-eye disease (FED) .

Phosphatidylcholine-sterol acyltransferase; Phospholipid-cholesterol acyltransferase and LACT; also named Lecithin-cholesterol acyltransferase; is an extracellular cholesterol esterifying enzyme which belongs to the AB hydrolase superfamily.

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.