Recombinant Human KLF6 Protein
Product Specifications
Background
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will result in gastric cancer and prostate cancer.
Abbreviation
KLF6
Synonyms
B-Cell-Derived Protein 1; BCD1; COPEB; CPBP; Core Promoter Element-Binding Protein; GC-Rich Sites-Binding Factor GBF; KLF6; Krueppel-Like Factor 6; Proto-Oncogene BCD1; ST12; Suppressor of Tumorigenicity 12 Protein; Transcription Factor Zf9
UniProt
Q99612
Accession Number
Q99612-3
Expression System
E.coli
Tag
None
Sequence
Met 1-Ser109
Field of Research
Epigenetics and nuclear signal; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
12.6 kDa
Observed Molecular Weight
13-19 kDa
Species
Human
Available Sizes
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