Recombinant Human KLF6 Protein

Product Specifications

Background

Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will result in gastric cancer and prostate cancer.

Abbreviation

KLF6

Synonyms

B-Cell-Derived Protein 1; BCD1; COPEB; CPBP; Core Promoter Element-Binding Protein; GC-Rich Sites-Binding Factor GBF; KLF6; Krueppel-Like Factor 6; Proto-Oncogene BCD1; ST12; Suppressor of Tumorigenicity 12 Protein; Transcription Factor Zf9

UniProt

Q99612

Accession Number

Q99612-3

Expression System

E.coli

Tag

None

Sequence

Met 1-Ser109

Field of Research

Epigenetics and nuclear signal; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.