Recombinant Human KLK-8/Kallikrein-8 Protein (His Tag)
Product Specifications
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Abbreviation
KLK-8; Kallikrein-8
Synonyms
KLK8; Kallikrein-8; NP; NRPN; Neuropsin; Ovasin; PRSS19; Serine Protease 19; Serine Protease TADG-14; TADG14; Tumor-Associated Differentially Expressed Gene 14 Protein; hK8
UniProt
O60259
Accession Number
AAH40887.1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gln29-GLy260
Field of Research
Signal Transduction; Cell biology; Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
26.0 kDa
Observed Molecular Weight
35 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Species
Human
Available Sizes
Documents
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