Recombinant Human Kallikrein 4/KLK4 Protein (His Tag)
Product Specifications
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Abbreviation
Kallikrein 4; KLK4
Synonyms
AI2A1; ARM1; EMSP; EMSP1; Enamel Matrix Serine Proteinase 1; KLK-L1; KLK4; Kallikrein-4; Kallikrein-Like Protein 1; PRSS17; PSTS; Prostase; Serine Protease 17; kallikrein
UniProt
Q9Y5K2
Accession Number
Q9Y5K2
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ser27-Ser254 (His197Gln)
Field of Research
Signal Transduction; Cell biology; Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
25.4 kDa
Observed Molecular Weight
25-32 kDa
Species
Human
Available Sizes
Documents
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