Recombinant Human ITIH3 Protein (His Tag)
Product Specifications
Background
ITIH3, which is short for Inter-alpha-trypsin inhibitor heavy chain H3, is a 890 aa. protein. It is secreted expression, and belongs to the ITIH family. I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin. ITTH3 may act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Abbreviation
ITIH3
Synonyms
ITI heavy chain H3; ITI-HC3; Inter-alpha-inhibitor heavy chain 3; Inter-alpha-trypsin inhibitor heavy chain H3; SHAP; Serum-derived hyaluronan-associated protein
UniProt
Q06033
Accession Number
Q06033
Expression System
HEK293 Cells
Tag
C-His
Sequence
Leu35-Asp651
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/zlr40g
Product MSDS
https://789.bio/eb/KeTWXH
Calculated Molecular Weight
70.4 kDa
Observed Molecular Weight
80-100 kDa
Species
Human
Available Sizes
Curated Selection
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