Recombinant Human Interleukin-9/IL-9 Protein (His Tag)

Product Specifications

Background

Interleukin-9 (IL-9) is a secreted protein that belongs to the IL-7/IL-9 family.Mature mouse IL-9 shares 57% and 74% amino acid sequence identity with human and rat IL-9, respectively. IL-9 supports IL-2 independent and IL-4 independent growth of helper T-cells. IL-9 stimulates cell proliferation and prevents apoptosis. It functions through the IL-9 receptor (IL-9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. IL-9 has been identified as a candidate gene for asthma. IL-9 is a determining factor in the pathogenesis of bronchial hyperresponsiveness.

Abbreviation

Interleukin-9; IL-9

Synonyms

Cytokine P; Interleukin; TCGF; IL9; HP40; IL-9; P40; Cytokine P40; Interleukin-9; P40 Cytokine; P40 T-cell and Mast Cell Growth Factor; T-cell Growth Factor P40; TCGF3; TCGFIII

UniProt

P15248

Accession Number

P15248

Expression System

HEK293 Cells

Tag

C-His

Sequence

Glu19-Ile144

Field of Research

Cancer; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.