Recombinant Human Interleukin-33/IL-33 Protein (His Tag)

Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils; Peyer patches and mesenteric lymph nodes; but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2) -associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP) ; activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.

DVS; IL1F; Interleukin; C9orf; IL-1F; IL33; C9orf26; DVS27; IL1F11; NF-HEV; NFEHEV; DVS27 related protein; IL-1F11; IL-33; Interleukin-1 family member 11; Interleukin-33; Nuclear factor from high endothelial venules; NFHEV; CHROMOSOME 9 OPEN READING FRAME 26; DKFZp586H0523; IL 1F11; IL 33; Interleukin 1 family member 11; Interleukin 33; INTERLEUKIN 33 NFHEV; Interleukin 33 precursor; Interleukin33; Interleukin-33 (109-270) ; NF HEV; Nuclear factor for high endothelial venules; OTTHUMP00000021041; RP11 575C20.2

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.