Recombinant Human Interleukin-3/IL-3 Protein (Human Cells, His Tag)
Product Specifications
Background
Interleukin-3 (IL-3) is a potent growth promoting cytokine. IL-3 can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. IL-3 exerts its biological function through binding to specific cell surface receptors. The amino acid sequences of this protein among different species share relatively low identity and its activity is highly species-specific. IL-3 has also been shown to possess neurotrophic activity; and is thought to be associated with neurologic disorders.
Abbreviation
Interleukin-3; IL-3
Synonyms
MLN; Interleukin; S100A; IL3; IL-3; MCGF; MULTI-CSF; Hematopoietic Growth Factor; Interleukin-3; Mast Cell Growth Factor; MCSF; Multipotential Colony-Stimulating Factor; P-Cell Stimulating Factor; P-Cell-Stimulating Factor; S100A11; MLN70; S100C
UniProt
P08700
Accession Number
P08700
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala20-Phe152
Applications
Cell culture
Field of Research
Immunology
Endotoxin
< 0.01 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.3-1. 5 ng/ml.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/kpeplp
Product MSDS
https://789.bio/eb/OyLOqH
Calculated Molecular Weight
16.1 kDa
Observed Molecular Weight
17-30 kDa
Species
Human
Available Sizes
Curated Selection
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