Recombinant Human IL-1 beta/IL1B Protein
Product Specifications
Background
IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Abbreviation
IL-1 beta; IL1B
Synonyms
IL1F; IL-1F; pro IL1F; IL-1; IL1-BETA; IL1F2; IL1 beta; IL1B; catabolin; IL-1B; pro Catabolin; pro IL1B; pro IL1F2; pro leukocytic endogenous mediator; pro leukocytic pyrogen; pro lymphocyte activating factor; pro mononuclear cell factor; IL-1F2; IL 1B; IL-1 beta
UniProt
P01584
Accession Number
P01584
Expression System
E.coli
Tag
C-His
Sequence
Ala117-Ser269
Applications
Cell culture
Field of Research
Cardiovascular; immunology; metabolism
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
503 x 107 IU/mg.7
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
18.5 kDa
Observed Molecular Weight
17 kDa
Species
Human
Available Sizes
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