Recombinant Human Interleukin-17F/IL-17F Protein

Product Specifications

Background

Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today; IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family; IL-17A through IL-17F; are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.

Abbreviation

Interleukin-17F; IL-17F

Synonyms

Cytokine ML; Interleukin; CANDF; IL17F; CANDF6; IL-17F; ML-1; ML1; Cytokine ML-1; IL24; IL-24; Interleukin-17F; Interleukin-24

UniProt

Q96PD4

Accession Number

Q96PD4

Expression System

E.coli

Tag

C-His

Sequence

Arg31-Gln163

Applications

Cell culture

Field of Research

Cardiovascular; Cancer; immunology

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.