Recombinant Human IGF-II/IGF2 Protein
Product Specifications
Background
Insulin-Like Growth Factor II (IGF2) belongs to the insulin family of polypeptide growth factors that is involved in development and growth. Members of this family are structurally homologous to proinsulin, and share higher sequence identity. IGF2 is expressed only from the paternally inherited allele and believed to be secreted by the liver and to circulate in the blood. IGF2 possess growth-promoting activity and can stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF2 is influenced by placental lactogen and may play a role in fetal development.
Abbreviation
IGF-II; IGF2
Synonyms
IGF-II; IGF2; Insulin-Like Growth Factor II; PP1446; Somatomedin-A
UniProt
P01344
Accession Number
P01344
Expression System
E.coli
Tag
N-His
Sequence
Ala25-Glu91
Applications
Cell culture
Field of Research
Signal Transduction; Cancer; Developmental Biology
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
50 3x 105 IU/mg.5
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/xqulh5
Product MSDS
https://789.bio/eb/SKOyjH
Calculated Molecular Weight
8.3 kDa
Observed Molecular Weight
11 kDa
Species
Human
Available Sizes
Curated Selection
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