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Recombinant Human PGRL/IGSF8 Protein (His Tag)

Product Specifications

Background

Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions.

Abbreviation

PGRL; IGSF8

Synonyms

CD316; CD81 Partner 3; CD81P3; EWI-2; EWI2; Glu-Trp-Ile EWI Motif-Containing Protein 2; IGSF8; IgSF8; Immunoglobulin Superfamily Member 8; KCT-4; KCT4; Keratinocytes-Associated Transmembrane Protein 4; LIR-D1; PGRL; Prostaglandin Regulatory-Like Protein

UniProt

Q969P0

Accession Number

Q969P0

Expression System

HEK293 Cells

Tag

C-His

Sequence

Arg28-Thr579

Field of Research

Microbiology; Cancer; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

59.6 kDa

Observed Molecular Weight

70-85 kDa

Species

Human

Available Sizes

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