Recombinant Human IL-20RB Protein (Fc Tag)

Interleukin-20 receptor subunit beta (IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22) . Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family

UNQ; PRO; MGC; DIRS; FNDC; fibronectin type III domain containing; IL-20R; IL20RB; DIRS1; FNDC6; IL-20R2; fibronectin type III domain containing 6; hCG_2022374; IL-20 receptor subunit beta; IL-20RB; IL-20R-beta; interleukin-20 receptor II; Interleukin-20 receptor subunit beta; MGC34923; UNQ557; PRO1114