Recombinant Human IL2RG/CD132 Protein (Fc & His Tag)

Product Specifications

Background

IL2RG contains one fibronectin type-III domain. IL2RG is an important signaling component of many interleukin receptors; including those of interleukin -2; -4; -7 and -21; and is thus referred to as the common gamma chain. IL2RG interacts with SHB upon interleukin stimulation and HTLV-1 accessory protein p12I. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) and severe combined immunodeficiency X-linked T-cell-negative /B-cell-positive / NK-cell-negative (XSCID) .

Abbreviation

IL2RG; CD132

Synonyms

IMD; IL2RG; CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1; Cytokine receptor common subunit gamma; gammaC; Interleukin-2 receptor subunit gamma; common &gamma- chain-n; IL-2R&gamma

UniProt

P31785

Accession Number

P31785

Expression System

HEK293 Cells

Tag

C-His

Sequence

Leu23-Ala262

Field of Research

Cancer; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.