Recombinant Human IL18RAP/IL1R7 Protein (His Tag)
Product Specifications
Background
IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
Abbreviation
IL18RAP; IL1R7
Synonyms
IL1R; ACPL; CD218b; CDw218b; IL-18RAcP; IL18RB; IL-18Rbeta; IL-18R-beta; IL-1R7; IL-1R-7; IL-1RAcPL; IL1R7; IL18RAP; IL-1RcPL; CDw218b; IL18Rβ Accessory protein like; Accessory protein-like; CD218 antigen-like family member B; I18RA; IL 18RAcP; IL 1R accessory protein like; IL 1R7; IL 1RAcPL; IL-18 receptor accessory protein; IL18Rbeta; IL-1R accessory protein-like; Interleukin 18 receptor accessory protein; Interleukin-1 receptor 7; Interleukin-18 receptor accessory protein; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta; Interleukin-18 receptor beta chain
UniProt
O95256
Accession Number
O95256
Expression System
HEK293 Cells
Tag
C-His
Sequence
Phe20-Arg356
Field of Research
Cancer; immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
39.4 kDa
Observed Molecular Weight
56 kDa
Formulation
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Species
Human
Available Sizes
Documents
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