Recombinant Human IL15RA/IL-15RA Protein (Fc Tag)
Product Specifications
Background
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.
Abbreviation
IL15RA; IL-15RA
Synonyms
MGC; IL15RA; CD215; alpha; CD215 antigen; IL-15 receptor subunit alpha; IL-15RA; IL-15R-alpha; interleukin 15 receptor; interleukin-15 receptor subunit alpha; MGC104179; AA690181; I15RA; IL 15R alpha; Interleukin 15 receptor alpha; Interleukin 15 receptor subunit alpha; sIL-15 receptor subunit alpha; sIL-15RA; sIL-15R-alpha; Soluble interleukin 15 receptor subunit alpha; Soluble interleukin-15 receptor subunit alpha
UniProt
Q13261
Accession Number
Q13261-3
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Ile31-Thr172
Applications
Cell culture
Field of Research
Signal Transduction; Cell biology; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
50
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
42.0 kDa
Observed Molecular Weight
60-75 kDa
Species
Human
Available Sizes
Documents
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