Recombinant Human IL-1RL2 Protein (His Tag)
Product Specifications
Background
Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene; belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A; IL36B and IL36G) . After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B; MAPK and other pathways.
Abbreviation
IL-1RL2
Synonyms
Interleukin-1 receptor-like; IL1RL; IL1RRP; IL-1Rrp; IL1R-rp; IL1RL2; IL-1Rrp2; IL-36R; IL1R-rp2; IL1RRP2; IL36R; IL-36 receptor; Interleukin-1 receptor-like 2
UniProt
Q9HB29
Accession Number
Q9HB29
Expression System
HEK293 Cells
Tag
C-His
Sequence
Asp20-Tyr337
Applications
BLI
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Loaded Anti-Human IL-36R mAb-Fc on Protein A Biosensor, can bind Human IL-1RL2-His with an affinity constant of 0.03 nM as determined in BLI assay.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/ogtaip
Product MSDS
https://789.bio/eb/uvLuTK
Calculated Molecular Weight
37.0 kDa
Observed Molecular Weight
60 kDa
Species
Human
Available Sizes
Curated Selection
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