Recombinant Human IL-1RL2 Protein (His Tag)

Product Specifications

Background

Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene; belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A; IL36B and IL36G) . After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B; MAPK and other pathways.

Abbreviation

IL-1RL2

Synonyms

Interleukin-1 receptor-like; IL1RL; IL1RRP; IL-1Rrp; IL1R-rp; IL1RL2; IL-1Rrp2; IL-36R; IL1R-rp2; IL1RRP2; IL36R; IL-36 receptor; Interleukin-1 receptor-like 2

UniProt

Q9HB29

Accession Number

Q9HB29

Expression System

HEK293 Cells

Tag

C-His

Sequence

Asp20-Tyr337

Applications

BLI

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Loaded Anti-Human IL-36R mAb-Fc on Protein A Biosensor, can bind Human IL-1RL2-His with an affinity constant of 0.03 nM as determined in BLI assay.

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.