Recombinant Human IL-1RAcP/IL1R3 Protein (Fc & His Tag)

Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1α; IL1βand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1; TOLLIP; MYD88; and IRAK1 or IRAK2. In addition; IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.

IL1R; Interleukin-1 Receptor; C3orf; IL-1 Receptor Accessory Protein; IL-1R3; IL-1R-3; IL-1RAcP; Interleukin-1 Receptor 3; Interleukin-1 Receptor Accessory Protein; C3orf13; IL1R3; IL1RAP; FLJ37788; IL 1 receptor accessory protein; IL 1R3; IL 1RAcP; IL 1RAP; Interleukin 1 Accessory Protein; interleukin 1 receptor 3; Interleukin 1 receptor accessory protein

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.