Recombinant Human IGF2BP2 Protein (His Tag, N-T7 Tag)
Product Specifications
Background
Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.
Abbreviation
IGF2BP2
Synonyms
Hepatocellular Carcinoma Autoantigen p62; IGF-II mRNA-Binding Protein 2; IGF2 mRNA-Binding Protein 2; IGF2BP2; IMP-2; IMP2; Insulin-Like Growth Factor 2 mRNA-Binding Protein 2; VICKZ Family Member 2; VICKZ2
UniProt
Q9Y6M1
Accession Number
Q9Y6M1
Expression System
E.coli
Tag
N-T7 & C-His
Sequence
Met 1-Thr 220
Field of Research
Signal Transduction; epigenetics and nuclear signal; immunology; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/qe9lw5
Product MSDS
https://789.bio/eb/80iLiL
Calculated Molecular Weight
27.2 kDa
Observed Molecular Weight
43 kDa
Species
Human
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
