Recombinant Human PLA2G16 Protein (His Tag)
Product Specifications
Background
Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models.
Abbreviation
PLA2G16
Synonyms
AdPLA; Adipose-Specific Phospholipase A2; Group XVI Phospholipase A1/A2; H-Rev 107 Protein Homolog; HRAS-Like Suppressor 1; HRAS-Like Suppressor 3; HRASLS3; HREV107; HREV107-1; HREV107-3; HRSL3; PLA2G16; Renal Carcinoma Antigen NY-REN-65
UniProt
P53816
Accession Number
P53816
Expression System
E.coli
Tag
N-His
Sequence
Asp12-Asp132
Field of Research
Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
14-17 kDa
Observed Molecular Weight
15 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50mM NaCl, 1mM EDTA, pH8.0.
Species
Human
Available Sizes
Curated Selection
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