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Recombinant Human GPD1/GDP-C Protein (Human Cells, His Tag)

Product Specifications

Background

Glycerol-3-Phosphate Dehydrogenase [NAD (+) ]; Cytoplasmic (GPDH-C) belongs to the NAD-Dependent Glycerol-3-Phosphate Dehydrogenase family. GPDH-C plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of Dihydroxyacetone Phosphate (DHAP) and reducing Nicotine Adenine Dinucleotide (NADH) to Glycerol-3-Phosphate (G3P) and NAD+. GPDH-C is inhibited by zinc ions and sulfate. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. GPDH-C is unlike Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) ; they have different substrates.

Abbreviation

GPD1; GDP-C

Synonyms

GPD-C; GPD1; GPDH-C; Glycerol-3-Phosphate Dehydrogenase [NAD (+) ] Cytoplasmic; HTGTI

UniProt

P21695

Accession Number

P21695

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met 1-Met349

Field of Research

Signal Transduction; Cardiovascular; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

38.6 kDa

Observed Molecular Weight

32-48 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 8.0.

Species

Human

Available Sizes

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