Recombinant Human GPD1/GDP-C Protein (Human Cells, His Tag)
Product Specifications
Background
Glycerol-3-Phosphate Dehydrogenase [NAD (+) ]; Cytoplasmic (GPDH-C) belongs to the NAD-Dependent Glycerol-3-Phosphate Dehydrogenase family. GPDH-C plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of Dihydroxyacetone Phosphate (DHAP) and reducing Nicotine Adenine Dinucleotide (NADH) to Glycerol-3-Phosphate (G3P) and NAD+. GPDH-C is inhibited by zinc ions and sulfate. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. GPDH-C is unlike Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) ; they have different substrates.
Abbreviation
GPD1; GDP-C
Synonyms
GPD-C; GPD1; GPDH-C; Glycerol-3-Phosphate Dehydrogenase [NAD (+) ] Cytoplasmic; HTGTI
UniProt
P21695
Accession Number
P21695
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met 1-Met349
Field of Research
Signal Transduction; Cardiovascular; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
38.6 kDa
Observed Molecular Weight
32-48 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 8.0.
Species
Human
Available Sizes
Curated Selection
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