Recombinant Human TSTA3/SDR4E1 Protein (His Tag)
Product Specifications
Background
GDP-L-Fucose Synthase is a NADP (H) -binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.
Abbreviation
TSTA3; SDR4E1
Synonyms
5-Epimerase-4-Reductase; GDP-4-Keto-6-Deoxy-D-Mannose-3; GDP-L-Fucose Synthase; Protein FX; Red Cell NADP (H) -Binding Protein; SDR4E1; Short-Chain Dehydrogenase/Reductase Family 4E Member 1; TSTA3
UniProt
Q13630
Accession Number
Q13630
Expression System
E.coli
Tag
C-His
Sequence
Met 1-Lys321
Field of Research
Signal Transduction; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
37.0 kDa
Observed Molecular Weight
40 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Species
Human
Available Sizes
Documents
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