Recombinant Human GFRRA2 Protein ((Fc & His Tag)

GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI) -linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signaling through the RET tyrosine kinase receptor. It acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1.

GDNF Family Receptor Alpha-2; GDNF Receptor Alpha-2; GDNF Receptor Beta; GDNFR-Alpha-2; GDNFR-Beta; GDNFRB; GFR-Alpha-2; GFRA2; NRTNR-Alpha; NTNR-Alpha; Neurturin Receptor Alpha; RET Ligand 2; RETL2; TGF-Beta-Related Neurotrophic Factor Receptor 2; TRNR2

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.