Recombinant Human Galectin-3/LGALS3 Protein (His Tag)
Product Specifications
Background
Galectin-3 (LGALS3) is also known as Galactose-specific lectin 3; Mac-2 antigen; Carbohydrate-binding protein 35; Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papillary carcinoma; and lowly during tumor progression. LGALS3 is probably forms homo- or heterodimers and secreted by a non-classical secretory pathway and associates with the cell surface. LGALS3 plays an important role during the acquisition of vasculogenic mimicry and angiogenic properties. LGLAS3 takes part in an immune regulator to inhibit T-cell immune responses and promote tumor growth; as a result providing a new mechanism for tumor immune tolerance.
Abbreviation
Galectin-3; LGALS3
Synonyms
35 kDa Lectin; CBP35; Carbohydrate-Binding Protein 35; GAL3; GALBP; GALIG; Gal-3; Galactose-Specific Lectin 3; Galactoside-Binding Protein; Galectin-3; IgE-Binding Protein; L-31; L31; LGALS2; LGALS3; Laminin-Binding Protein; Lectin L-29; MAC2; Mac-2 Antigen; P35
UniProt
P17931
Accession Number
AAH53667.1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala2-Ile250
Field of Research
Cell biology; Neuroscience
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
27.2 kDa
Observed Molecular Weight
35 kDa
Species
Human
Available Sizes
Curated Selection
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