Recombinant Human Interleukin-13/IL-13 Protein (Fc Tag)
Product Specifications
Background
Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα ) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2) . As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.
Abbreviation
Interleukin-13/IL-13
Synonyms
ALRH; IL-13; IL13; P600
Accession Number
AAK53823.1
Expression System
HEK293 Cells
Tag
N-hFc
Sequence
Gly 21-Asn 132
Applications
ELISA
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
Immobilized recombinant human IL13RA2 at 8 μg/ml (100 μl/well) can bind IL13 with a linear range of 0.25-8.0 ng/ml.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/vslew1
Product MSDS
https://789.bio/eb/qDSu10
Calculated Molecular Weight
39.0 kDa
Observed Molecular Weight
50-55 kDa
Species
Human
Available Sizes
Curated Selection
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