Recombinant Human Follitropin Subunit β/FSHB Protein (His Tag)

Product Specifications

Background

Follitropin Subunit β (FSHB) is a secreted protein that belongs to the glycoprotein hormones subunit β family. The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. FSHB exists in a heterodimer of a common α chain and an unique β chain that confers biological specificity to thyrotropin, lutropin, follitropin, and gonadotropin. FSHB stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD) .

Abbreviation

Follitropin Subunit β; FSHB

Synonyms

FSH-B; FSH-Beta; FSHB; Follicle-Stimulating Hormone Beta Subunit; Follitropin Beta Chain; Follitropin Subunit Beta

UniProt

P01225

Accession Number

P01225

Expression System

HEK293 Cells

Tag

C-His

Sequence

Asn19-Glu129

Field of Research

Signal Transduction; Cancer; Developmental Biology; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.