Recombinant Human FSH Protein (Flag & His Tag)
Product Specifications
Background
Human Follicle-stimulating hormone (FSH) is a member of glycoprotein hormones subunit beta family, whichalso includes LH, chorionic gonadotropin (CG) and thyroid-stimulating hormone (TSH) . FSH and its familymembers are heterodimers consisting of non-covalently linked α- and β-subunits. They share an identical αsubunit, and β-subunits vary. FSH has a unique β-subunit (FSHβ), which confers its specific biologic activityand is responsible for interaction with the FSH-receptor which belongs to a subfamily of GPCRs calledleucine-rich-repeat-containing GPCRs (LGRs) . FSH is secreted from the pituitary gland and regulatesreproduction in mammals. FSH stimulates sertoli cell proliferation in testes and supports spermatogenesis inmales, and induces the maturation of ovarian follicles in females.
Abbreviation
FSH
Synonyms
FSH; FSH alpha/beta; Follicle-stimulating hormone
UniProt
P01215; P01225
Accession Number
P01215&P01225
Expression System
HEK293 Cells
Tag
C-Flag-His
Sequence
Ala25-Ser116&Asn19-Glu129
Field of Research
Signal Transduction; Neuroscience; Cancer; Developmental Biology; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/lsrxi5
Product MSDS
https://789.bio/eb/rTCiLK
Calculated Molecular Weight
11.5&13.5 kDa
Observed Molecular Weight
20-30 kDa
Species
Human
Available Sizes
Curated Selection
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