Recombinant Human FGF-7/KGF Protein
Product Specifications
Background
Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities; and are involved in a variety of biological processes; including embryonic development; cell growth; morphogenesis; tissue repair; tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor; whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.
Abbreviation
FGF-7; KGF
Synonyms
FGF-7; FGF7; Fibroblast growth factor 7; HBGF-7; Heparin-binding growth factor 7; KGF; Keratinocyte growth factor
UniProt
P21781
Accession Number
P21781
Expression System
E.coli
Tag
None
Sequence
Cys32-Thr194
Field of Research
Signal Transduction; Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
18.9 kDa
Observed Molecular Weight
17 kDa
Species
Human
Available Sizes
Documents
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