Recombinant Human FGF-2/FGFb Protein
Product Specifications
Background
Fibroblast growth factor 2 (FGF2) is a secreted protein and belongs to the heparin-binding growth factors family. FGF2 is produced by epithelial; tumor and other cell types. It involved in developmental processes and regulates differentiation; proliferation; and migration; FGF2 is a critical factor for growing embryonic stem cells in culture without inducing differentiation. FGF2 has a high affinity for heparan sulfate and binding is a step in the FGF basic activation of FGFR tyrosine kinase.
Abbreviation
FGF-2; FGFb
Synonyms
Basic fibroblast growth factor; Bfgf; FGF-2; FGF2; FGFB; Fibroblast growth factor 2; HBGF-2; Heparin-binding growth factor 2
UniProt
P09038
Accession Number
P09038
Expression System
E.coli
Tag
N-His
Sequence
Ala 135-Ser 288
Applications
Cell culture
Field of Research
Signal Transduction; Cardiovascular; Neuroscience; Cancer; Developmental Biology; Stem cells
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
505 x 105 IU/mg.5
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
18.1 kDa
Observed Molecular Weight
17 kDa
Species
Human
Available Sizes
Documents
Frequently Asked Questions
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