Recombinant Human FIBP Protein
Product Specifications
Background
Acidic Fibroblast Growth Factor Intracellular-Binding Protein (FIBP) is highly expressed in the heart, skeletal muscle, and pancreas. Acidic Fibroblast Growth Factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FIBP is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF) . It is postulated that FIBP may be involved in the mitogenic action of aFGF.
Abbreviation
FIBP
Synonyms
Acidic Fibroblast Growth Factor Intracellular-Binding Protein; FGF-1 Intracellular-Binding Protein; FIBP; aFGF Intracellular-Binding Protein
UniProt
O43427
Accession Number
NP_004205.2
Expression System
E.coli
Tag
None
Sequence
Met 1-Asp357
Field of Research
Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
41.8 kDa
Observed Molecular Weight
40-50 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, pH8.0.
Species
Human
Available Sizes
Documents
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