Recombinant Human ETS1/EWSR2 Protein (His Tag)
Product Specifications
Background
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death Associated Protein 6.
Abbreviation
ETS1; EWSR2
Synonyms
ETS1; ETS1 Protein; Isoform CRA_a; Protein C-ets-1; V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) ; hCG_1732038
UniProt
P14921
Accession Number
P14921-5
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Thr 272
Field of Research
Epigenetics and Nuclear Signaling, Cancer, Cardiovascular
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
33.0 kDa
Observed Molecular Weight
38 kDa
Species
Human
Available Sizes
Documents
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