Recombinant Human ETS1/EWSR2 Protein (His Tag)

Product Specifications

Background

ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death Associated Protein 6.

Abbreviation

ETS1; EWSR2

Synonyms

ETS1; ETS1 Protein; Isoform CRA_a; Protein C-ets-1; V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) ; hCG_1732038

UniProt

P14921

Accession Number

P14921-5

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Thr 272

Field of Research

Epigenetics and Nuclear Signaling, Cancer, Cardiovascular

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.