Recombinant Human ERP44 Protein (His Tag)
Product Specifications
Background
Endoplasmic reticulum resident protein 44 (TXNDC4) is is a 406 amino acid protein that contains one thioredoxin domain. TXNDC4 mediates thiol-dependent retention in the early secretory pathway and forms mixed disulfides with substrate proteins through its conserved CRFS motif.It can inhibit the calcium channel activity of ITPR1.It may have a role in the control of oxidative protein folding in the endoplasmic reticulum.
Abbreviation
ERP44
Synonyms
ER protein 44; KIAA0573; TXNDC4; Thioredoxin domain-containing protein 4
UniProt
Q9BS26
Accession Number
Q9BS26
Expression System
HEK293 Cells
Tag
C-His
Sequence
Glu30-Asp402
Field of Research
Signal Transduction; Cell biology; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
44.2 kDa
Observed Molecular Weight
50 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 7.5.
Species
Human
Available Sizes
Documents
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