Recombinant Human Ephrin-B2/EFNB2 Protein (His Tag)

Product Specifications

Background

Ephrin-B2 is a type I transmembrane protein and belongs the Ephrin family. It binds to the receptor tyrosine kinases, such as EPHA4, EPHB4 and EPHA3. Ephrin-B2 has been implicated in mediating developmental events, especially in the nervous system, erythropoiesis and tumour metastasis. Ligation of Ephrin-B2 with complementary EphB receptors on adjacent cells results in a combination of forward (EphB receptors) and reverse (Ephrin-B2) signalling, which is central to tissue development and remodelling functions. In addition, Ephrin-B2 may play a role in constraining the orientation of longitudinally projecting axons.

Abbreviation

Ephrin-B2; EFNB2

Synonyms

EFNB2; EPH-Related Receptor Tyrosine Kinase Ligand 5; EPLG5; Ephrin-B2; HTK Ligand; HTK-L; HTKL; LERK-5; LERK5

UniProt

P52799

Accession Number

P52799

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ile28-Ala229

Field of Research

Cell biology; Cardiovascular; Neuroscience; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.