Recombinant Human Ephrin-A5/EFNA5 Protein (Fc Tag)
Product Specifications
Background
Ephrin-A5 (EFNA5) belongs to the ephrin family, contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.
Abbreviation
Ephrin-A5; EFNA5
Synonyms
AL-1; EFNA5; EPH-related receptor tyrosine kinase ligand 7; EPLG7; Ephrin-A5; LERK-7; LERK7
UniProt
P52803
Accession Number
P52803
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Gln21-Asn203
Field of Research
Signal Transduction; Neuroscience
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/kcgt9r
Product MSDS
https://789.bio/eb/r1ePyP
Calculated Molecular Weight
48.3 kDa
Observed Molecular Weight
55-60 kDa
Species
Human
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
