Recombinant Human Ephrin-A4/EFNA4 Protein (Fc & His Tag)
Product Specifications
Background
Ephrin-A4 is a member of the ephrin ligand family which binds members of the Eph receptor family. All ligands share a conserved extracellular sequence; which most likely corresponds to the receptor binding domain. Ephrin-A4 consists of approximately 125 amino acids and includes four invariant cysteines; It has been shown to bind EphA2; EphA3; EphA4; EphA5; EphA6; EphA7; and EphB1. Ephrin-A4 binds promiscuously Eph receptors residing on adjacent cells; leading to contact-dependent bidirectional signaling into neighboring cells. It may play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.
Abbreviation
Ephrin-A4; EFNA4
Synonyms
EFNA4; EPH-Related Receptor Tyrosine Kinase Ligand 4; EPLG4; Ephrin-A4; LERK-4; LERK4
UniProt
P52798
Accession Number
P52798
Expression System
HEK293 Cells
Tag
C-Fc-His
Sequence
Leu26-Gly171
Applications
ELISA
Field of Research
Cardiovascular; Neuroscience; Developmental Biology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Immobilized Human EphA7-His (Cat: PKSH033689) at 2μg/ml (100 μl/well) can bind Human EFNA4-Fc-6His. The ED50 of Human EFNA4-Fc-6His is 1. 5190 ug/ml.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/4rgv1r
Product MSDS
https://789.bio/eb/K48yTC
Calculated Molecular Weight
44.3 kDa
Observed Molecular Weight
45 kDa
Species
Human
Available Sizes
Curated Selection
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