Recombinant Human Ephrin-A1/EFNA1 Protein (His Tag)

Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.

EFNA1; EPH-Related Receptor Tyrosine Kinase Ligand 1; EPLG1; Ephrin-A1; Immediate Early Response Protein B61; LERK-1; LERK1; TNF Alpha-Induced Protein 4; TNFAIP4; Tumor Necrosis Factor Alpha-Induced Protein 4

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.